GLYCO-IMMUNE CHECKPOINT INHIBITORS
Targeting Glycan-Sensing Checkpoints to Unleash Both the Innate and Adaptive Immune Responses to Cancer

GLYCO-IMMUNE CHECKPOINT INHIBITORS

The Need

Despite the early success of first-generation immuno-oncology drugs, most cancer patients still do not achieve clinical responses.

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The Scientific Opportunity

Cell surface glycosylation is now known to play a central role in immuno-oncology: Tumor cells evolve over time, cloaking themselves in certain glycan patterns that down-regulate a wide spectrum of innate and adaptive immune cell types which are critical to fighting cancer.

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The Approach

Palleon Pharmaceuticals has integrated technologies and insights from world-renowned scientific leaders in glycoscience and human immunology to create the first Glyco-Immune Checkpoint Inhibitors to treat cancer patients.

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Our EAGLE platform enables the development of drugs that inhibit #GlycoImmuneCheckpoints by disabling the immunosup… http://5iBF2ZpN2J

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What does the role of sialic acid play in #cancer? Check out @elandhuis's paper in @ScienceNews, citing… http://lhxBg5nyir

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Our Founding Science

Hear from Dr. Carolyn Bertozzi on glycoscience, Glyco-Immune Checkpoints, and how Palleon is positioned to advance this unexplored area of immuno-oncology to benefit patients.

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