GLYCO-IMMUNE CHECKPOINT INHIBITORS
Targeting Glycan-Sensing Checkpoints to Unleash Both the Innate and Adaptive Immune Responses to Cancer
GLYCO-IMMUNE CHECKPOINT INHIBITORS
The Need
Despite the early success of first-generation immuno-oncology drugs, most cancer patients still do not achieve clinical responses.
The Scientific Opportunity
Cell surface glycosylation is now known to play a central role in immuno-oncology: Tumor cells evolve over time, cloaking themselves in certain glycan patterns that down-regulate a wide spectrum of innate and adaptive immune cell types which are critical to fighting cancer.
The Approach
Palleon Pharmaceuticals has integrated technologies and insights from world-renowned scientific leaders in glycoscience and human immunology to create the first Glyco-Immune Checkpoint Inhibitors to treat cancer patients.
News
Palleon Pharmaceuticals Announces Successful Defense of European Patent
November 26, 2018Palleon Pharmaceuticals Announces Preclinical Data from EAGLE Platform to be Presented at the AACR Special Conference on Tumor Immunology and Immunotherapy
Twitter
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Our EAGLE platform enables the development of drugs that inhibit #GlycoImmuneCheckpoints by disabling the immunosup… http://5iBF2ZpN2J
@Palleon_Pharma
What does the role of sialic acid play in #cancer? Check out @elandhuis's paper in @ScienceNews, citing… http://lhxBg5nyir