GLYCO-IMMUNE CHECKPOINT INHIBITORS
Targeting Glycan-Sensing Checkpoints to Unleash Both the Innate and Adaptive Immune Responses to Cancer

GLYCO-IMMUNE CHECKPOINT INHIBITORS

Immuno-Oncology Today:
An Unmet Need

Despite the early success of first-generation immuno-oncology drugs, most cancer patients do not respond to these treatments or eventually develop resistance.

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Our Science

Cell surface glycosylation is now known to play a central role in tumor immune evasion: Tumor cells evolve to express distinct immunosuppressive glycan patterns on their surfaces that down-regulate a wide spectrum of innate and adaptive immune cell types, which are critical for a coordinated anti-tumor immune response.

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The Approach

Palleon Pharmaceuticals is the leading biotechnology company developing drugs to treat cancer by targeting glyco-immune checkpoints, which are glycan-sensing inhibitory receptors found on innate and adaptive immune cells.

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This week is #WorldPharmaWeek and we look forward to discussing the highlights in #immunooncology from… http://Z9OnjfAEPK

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#DYK that every tumor has a unique glycan signature? By deciphering the tumor glyco-code, Palleon is working to mat… http://A58eHqMaeM

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Our Founding Science

Hear from Dr. Carolyn Bertozzi on glycoscience, Glyco-Immune Checkpoints, and how Palleon is positioned to advance this unexplored area of immuno-oncology to benefit patients.

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